Pharmacology of bronchodilators.
نویسنده
چکیده
In the UK, diseases that cause airflow obstruction are common. About 5.1 million people receive treatment for asthma and about 600,000 people are diagnosed as having chronic obstructive pulmonary disease (COPD), although this is likely to be an underestimate (British Thoracic Society, 2001).
منابع مشابه
Pharmacology and therapeutics of bronchodilators.
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of the current management of chronic obstructive pulmonary disease (COPD) and are critical in the symptomatic management of asthma, although controversies around the use of these drugs remain. Bronchodilators work through their direct relaxation effect on airway smooth muscle cells. at present, three maj...
متن کاملThe use of bronchodilators in the treatment of airway obstruction in elderly patients.
Ageing is associated with important anatomical, physiological and psychosocial changes that may have an impact on the management of obstructive airway diseases (asthma and chronic obstructive pulmonary disease (COPD)) and on their optimal therapy. Ageing-related modifications might be responsible for a different effectiveness of bronchodilators in the elderly patients as compared to younger sub...
متن کاملTiotropium bromide
Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not been shown to alter the rate of decline in FEV...
متن کاملPharmacology of bronchodilators used in the treatment of COPD.
Anticholinergics have been used as bronchodilators for several hundred years in western Europe (7). They act by blocking the effects of acetylcholine, which is released from parasympathetic nerves in the airways, and which contributes to bronchoconstriction and mucus secretion in patients with COPD. Acetylcholine causes activation of muscarinic receptors at the level of the target cells, such a...
متن کاملAssessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD.
The long-acting inhaled bronchodilators available for use in chronic obstructive pulmonary disease (COPD) vary in their pharmacological class (β2-adrenergic agonist or antimuscarinic/anticholinergic, alone or combined), durations of action and speed of onset of bronchodilator effect. In the early stages of development of a maintenance bronchodilator, the goals are to identify a molecule with th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Nursing times
دوره 100 6 شماره
صفحات -
تاریخ انتشار 2004